PBN

PBN VITASPACE.COM

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3376-24-7-s5g

PBN = (N-tert-Butyl--phenylnitrone) (99+%)

5 g

146.00

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PBN = N-tert-Butyl--phenylnitrone = Phenyl Butyl Nitrone (CAS# = 3376-24-7)

Chemical Formula = C₁₁H₁₅NO

Assay = 99+% HPLC

The health effects of this chemical have not been fully determined. This chemical is for laboratory use only, not for drug or household use.

REFERENCES for PBN

A spin trap, N-tert-butyl-alpha-phenylnitrone [PBN] extends the life span of mice. Biosci Biotechnol Biochem 1998 Apr;62(4):792-4

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts. Free Radic Biol Med 2000 Jan 1;28(1):64-74 [Click to read]

Reversal of Age-Related Increase in Brain Protein Oxidation, Decrease in Enzyme Activity, and Loss in Temporal and Spatial Memory by Chronic Administration of the Spin-Trapping Compound N-Tert-Butyl-- Phenylnitrone [PBN] Proceedings of the National Academy of Sciences, Vol 88, 3633-3636, Copyright � 1991 by National Academy of Sciences

Systemic Administration of Phenyl-N-tert-Butylnitrone [PBN] Protects the Retina from Light Damage Investigative Ophthalmology and Visual Science. 2001;42:1375-1379

Alpha-Phenyl-tert-butyl-nitrone [PBN] attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: an EPR study Free Radic Res Commun 1993;19(4):255-65

The spin-trap N-tert-alpha-phenyl-butylnitrone [PBN] prolongs the life span of the senescence accelerated mouse Biochem Biophys Res Commun 1995 Jun 26;211(3):847-9

Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl--phenylnitrone [PBN] Proc. Natl. Acad. Sci. USA Vol. 94, pp. 674-678, January 1997 Medical Sciences