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Read the REFERENCES for NtBHA at the bottom of this page or ORDER using the information below.
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57497-39-9-s5g |
NtBHA = N-tert-Butyl hydroxylamine HCl (100%) |
5 g |
149.00 |
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NtBHA = N-tert-Butyl hydroxylamine HCl (CAS# = 57497-39-9)
Chemical Formula = HONHC(CH3)3·HCl
Assay = 100% by Titrimetric Analysis
Molecular Weight = 125.6
The health effects of this chemical have not been fully determined. This chemical is for laboratory use only, not for drug or household use.
REFERENCES for NtBHA
Click on the links to read the abstracts or full articles. Note that references for PBN are also listed since NtBHA is the active moiety of PBN.
N-t-Butyl
Hydroxylamine [NtBHA], a Hydrolysis Product of 
-Phenyl-N-t-butyl
Nitrone, Is More Potent in Delaying Senescence in Human Lung Fibroblasts
J Biol Chem, Vol. 275, Issue 10, 6741-6748, March 10, 2000
N-t-Butyl hydroxylamine [NtBHA] is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro. FASEB J 2001 Oct;15(12):2196-204
Changes in myosin structure
and function in response to glycation. [NtBHA]
FASEB J 2001 Nov;15(13):2415-22
On the "struggle between chemistry and biology during aging"--implications for DNA repair, apoptosis and proteolysis, and a novel route of intervention. [NtBHA] Biogerontology 2001;2(3):173-8
The use of N-t-butyl hydroxylamine for radioprotection in cultured cells and mice. [Click to read]
Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. [Click to read]
A spin trap, N-tert-butyl-alpha-phenylnitrone [PBN] extends the life span of mice. Biosci Biotechnol Biochem 1998 Apr;62(4):792-4
Accumulation of
single-strand breaks is the major cause of telomere shortening in human
fibroblasts. Free Radic Biol Med 2000 Jan
1;28(1):64-74 [Click
to read]
Reversal
of Age-Related Increase in Brain Protein Oxidation, Decrease in Enzyme Activity,
and Loss in Temporal and Spatial Memory by Chronic Administration of the
Spin-Trapping Compound N-Tert-Butyl--
Phenylnitrone [PBN]
Proceedings of the National Academy of Sciences, Vol 88,
3633-3636, Copyright © 1991 by National Academy of Sciences
Alpha-Phenyl-tert-butyl-nitrone [PBN] attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: an EPR study Free Radic Res Commun 1993;19(4):255-65
The spin-trap N-tert-alpha-phenyl-butylnitrone [PBN] prolongs the life span of the senescence accelerated mouse Biochem Biophys Res Commun 1995 Jun 26;211(3):847-9
Free radical oxidation of brain proteins in accelerated senescence and its
modulation by N-tert-butyl--phenylnitrone
[PBN]
Proc. Natl. Acad. Sci. USA
Vol. 94, pp. 674-678, January 1997 Medical Sciences
Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone. [Click to read]
Nitrone-based free radical traps as
neuroprotective agents in cerebral ischaemia and other pathologies. [Click
to read]